Cholestasis

From Freepedia

In medicine, cholestasis is a condition where bile can not flow from from the liver to the duodenum.

Contents 1 Etiology 2 Symptoms 3 Also see 4 External links

Etiology

• gallstones
• abdominal mass (e.g. cancer)
• primary sclerosis cholangitis, secondary to inflammatory bowel disease
• Primary biliary cirrhosis, secondary to autoimmune disorders
• congential anomalies of the bilary tract
• biliary trauma

Symptoms

• Pale stools,
• dark urine,
• itchiness (pruritis) and
• jaundice.

Bile is secreted by the liver to aid in the digestion of fats. Drugs such as golds salts,nitrofurantoin, anabolic steroids, chlorpromazine, prochlorperazine, sulindac, cimetidine, erythromycin, can cause cholestasis and may result in damage to the liver.

Also see

• Liver function tests

External links

• Drug-induced cholestasis - medlineplus.org
• Cholestasis - emedicine.com