Suppository

From Freepedia

A suppository is a medicine that is inserted either into the rectum (rectal suppository) or into the vagina (vaginal suppository) where it melts. The alternative term for delivery of medicine via such routes, is as a pharmaceutical pessary.

Vaginal suppositories are used to treat gynaecological ailments, especially vaginal infections such as candidiasis, or as vaginal contraceptives.

Rectal suppositories are used:

• For laxative purposes, with chemicals such as glycerin, bisacodyl or as CO₂ laxative.
• To treat a hemorrhoid by delivering a moisturizer or vasoconstrictor.
• For general medical administration purposes: the substance crosses the rectal mucosa into the bloodstream; examples include paracetamol and eucalyptol suppositories.

Except for glycerin suppositories, suppositories are made of a greasy excipient (formerly, cocoa butter) in which the active substance is diluted. This may be a source of discomfort for the patient, as the melted excipient may pass the anus during flatulences.

Suppositories are used especially for small child patients, for they may be easier to administer than tablets or syrups.