Trypanosome

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Trypanosomes
Image:Trypanosoma cruzi crithidia.jpeg
Trypanosoma cruzi parasites
Scientific classification
Kingdom:Protista
Phylum:Euglenozoa
Class:Kinetoplastea
Order:Trypanosomatida
Genera

Blastocrithidia
Crithidia
Endotrypanum
Herpetomonas
Leishmania
Leptomonas
Phytomonas
Trypanosoma
Wallaceina

Trypanosomes are a group of kinetoplastid protozoa, distinguished by having only a single flagellum. All members are exclusively parasitic, found primarily in insects. A few genera have life-cycles involving a secondary host, which may be a vertebrate or a plant. These include several species that cause major diseases in humans.

The most notable trypanosomal diseases are sleeping sickness, Chagas disease, and leishmaniasis. These first two are caused by species of Trypanosoma and the last by Leishmania, which are the main genera that infect vertebrates. Species that infect plants are classified as Phytomonas.

A variety of different forms appear in the life-cycles of trypanosomes, distingished mainly by the position of the flagellum:

Amastigote (leishmanial) - reduced or absent
Promastigote (leptomonad) - anterior of nucleus, free from cell body
Epimastigote (crithidial) - anterior of nucleus, connected by a short undulating membrane
Opisthomastigote (herpetomonad) - posterior of nucleus, passing through a long groove in the cell
Trypomastigote (trypanosomal) - posterior of nucleus, connected by a long undulating membrane

All trypanosomes have at least amastigote and promastigote stages. Trypanosoma appears in all five forms, with the trypanosomal stage occurring in the vertebrate host.



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