Viloxazine
From Freepedia
| 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine[1] | |
| CAS number ? | ATC code N06AX09 |
| Chemical formula | ? |
| Molecular weight | ? |
| Bioavailability | ? |
| Metabolism | ? |
| Elimination half-life | ? |
| Time to reach steady state | 5 days |
| Excretion | Renal[2] |
| Pregnancy category | ? |
| Legal status | Not a controlled substance |
| Route(s) of administration | Oral |
| Formulation(s) | ? |
Drug Interactions
Viloxazine is known to increase plasma levels of phenytoin by an average of 37%.[6]
References
- ^ Nattrass, Chris. Detection and Confirmation of Viloxazine Testing Integrity Program, Inc.
- ^ Case DE, Reeves PR. "The disposition and metabolism of I.C.I. 58,834 (viloxazine) in humans." Xenobiotica. 1975 Feb;5(2):113-29. PMID 1154799
- ^ 【合法】個人輸入代行薬【未認可】 (The relevant section is English)
- ^ Muller-Oerlinghausen B, Ruther E. "Clinical profile and serum concentration of viloxazine as compared to amitriptyline." Pharmakopsychiatr Neuropsychopharmakol. 1979 Jul;12(4):321-37. PMID 386390
- ^ F Pisani, A Fazio, C Artesi, M Russo, R Trio, G Oteri, E Perucca and R Di Perri. "Elevation of plasma phenytoin by viloxazine in epileptic patients: a clinically significant drug interaction." Journal of Neurology, Neurosurgery, and Psychiatry, 1992, Vol 55, 126-127 PMID 1538217
- ^ Lloyd KG, Thuret F, Pilc A. "Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock." J Pharmacol Exp Ther. 1985 Oct;235(1):191-9. PMID 2995646
